| Last Name | First Name | Number | Year | Company | Image | |
| Easler | Mike | 395 | 1986 | Donruss | View Card | |
| Easterly | Jamie | 623 | 1982 | Donruss | View Card | |
| Easterly | Jamie | 31 | 1983 | Fleer | View Card | |
| Edwards | Johnny | 178 | 1963 | Topps | View Card | |
| Egan | Jonathan | AFL7 | 2005 | Bowman AFL | View Card | |
| Eichhorn | Mark | 13 | 1986 | Donruss Rookies | View Card | |
| Eichhorn | Mark | 34T | 1986 | Topps Traded | View Card | |
| Eichhorn | Mark | 321 | 1987 | Donruss | View Card | |
| Eichhorn | Mark | 371 | 1987 | O-Pee-Chee | View Card | |
| Eichhorn | Mark | 28T | 1990 | Topps Traded | View Card | |
| Eichhorn | Mark | U77 | 1990 | Fleer Update | View Card | |
| Eiland | Dave | 8 | 1989 | Topps | View Card | |
| Elbert | Scott | 128 | 2009 | Topps Heritage | View Card | |
| Eldred | Cal | 327 | 1992 | Stadium Club | View Card | |
| Elia | Lea | 32T | 1987 | Topps Traded | View Card | |
| Elia | Lee | 32T | 1987 | Topps Traded | View Card | |
| Ellsbury | Jacoby | 9 | 2007 | Pawtucket Red Sox | View Card | |
| Ellsworth | Steve | 180 | 1987 | TCMA Pawtucket Red Sox | View Card | |
| Ellsworth | Steve | 54 | 1988 | Donruss Rookies | View Card | |
| Ellsworth | Steve | 83T | 1988 | Score Update | View Card | |
| Ellsworth | Steve | 704 | 1989 | Procards Pawtucket Red Sox | View Card | |
| Ellsworth | Steve | 7 | 1989 | CMC Pawtucket Red Sox | View Card | |
| Elster | Kevin | 34 | 1988 | Donruss Rookies | View Card | |
| Elster | Kevin | 624 | 1988 | Score Update | View Card | |
| Elster | Kevin | U104 | 1988 | Fleer Update | View Card | |
| Engel | Reid | BDP70 | 2006 | Bowman Gold | View Card | |
| Engel | Reid | BDP70 | 2006 | Bowman | View Card | |
| Ensberg | Morgan | 437 | 2003 | Topps | View Card | |
| Ensberg | Morgan | 199 | 2007 | Fleer | View Card | |
| Eppard | Jim | U13 | 1988 | Fleer Update | View Card | |
| Erickson | Roger | 553 | 1982 | Fleer | View Card | |
| Erickson | Roger | 30T | 1982 | Topps Traded | View Card | |
| Erskine | Carl | 12 | 1983 | 1953 Bowman Reprint | View Card | |
| Erskine | Carl | -- | ---- | Baseball's All Time Greats | View Card | |
| Erskine | Carl | -- | ---- | Self-Published | View Card | |
| Ethier | Andre | 129 | 2007 | Goudey | View Card | |
| Evans | Darrell | 533 | 1989 | Donruss | View Card | |
| Evans | Dwight | 184 | 1987 | Donruss Opening Day | View Card | |
| Evans | Dwight | -- | 1988 | Starting Lineup | View Card | |
| Exposito | Luis | 58 | 2008 | Donruss Threads | View Card | |
| Exposito | Luis | 58 | 2008 | Donruss Threads | View Card | |
| Exposito | Luis | 23 | 2009 | Salem Red Sox | View Card | |
| Exposito | Luis | 23 | 2010 | Portland Sea Dogs | View Card | |